Who Holds Amylyx Pharmaceuticals, Inc. (AMLX)? 207 Institutional Holders, Q2 2026
Managers with more than $100 million in US equities report their holdings on Form 13F within 45 days of each quarter end. Quarter ended 30 Jun 2026: 207 holders, $2.1 billion in total.
Largest holders
The 100 largest by value. Change in shares against Q1 2026.
| Manager | Shares | Value | Change | |
|---|---|---|---|---|
| FMR LLC | 16,727,909 | $300 million | +1% | 13F |
| BlackRock, Inc. | 8,827,085 | $159 million | 0% | 13F |
| PERCEPTIVE ADVISORS LLC | 8,334,882 | $150 million | +1% | 13F |
| TCG Crossover Management, LLC | 6,243,812 | $112 million | +0% | 13F |
| Commodore Capital LP | 5,650,000 | $101 million | +0% | 13F |
| Jupiter Topco LLC | 5,236,102 | $94 million | New | 13F |
| Saturn V Capital Management LP | 4,624,101 | $83 million | +6% | 13F |
| VANGUARD CAPITAL MANAGEMENT LLC | 4,224,224 | $76 million | +2% | 13F |
| MORGAN STANLEY | 3,130,808 | $56 million | +44% | 13F |
| Driehaus Capital Management LLC | 3,036,970 | $55 million | +2% | 13F |
| First Light Asset Management, LLC | 3,023,256 | $54 million | -5% | 13F |
| FRANKLIN RESOURCES INC | 2,950,225 | $53 million | +30% | 13F |
| GOLDMAN SACHS GROUP INC | 2,858,239 | $51 million | +9% | 13F |
| STATE STREET CORP | 2,603,337 | $47 million | +10% | 13F |
| GEODE CAPITAL MANAGEMENT, LLC | 2,335,315 | $42 million | +6% | 13F |
| JPMORGAN CHASE & CO | 1,863,650 | $35 million | +1067% | 13F |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 1,900,000 | $34 million | -47% | 13F |
| Siren, L.L.C. | 1,480,586 | $27 million | +20% | 13F |
| EVENTIDE ASSET MANAGEMENT, LLC | 1,327,536 | $24 million | -12% | 13F |
| 683 Capital Management, LLC | 1,279,512 | $23 million | -16% | 13F |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 1,061,534 | $19 million | +12% | 13F |
| Alyeska Investment Group, L.P. | 1,053,015 | $19 million | New | 13F |
| Almitas Capital LLC | 974,881 | $18 million | -54% | 13F |
| DIMENSIONAL FUND ADVISORS LP | 902,463 | $16 million | 0% | 13F |
| Jones Hill Capital LP | 894,058 | $16 million | -44% | 13F |
| Woodline Partners LP | 846,387 | $15 million | +0% | 13F |
| NORTHERN TRUST CORP | 831,740 | $15 million | +7% | 13F |
| BANK OF AMERICA CORP /DE/ | 821,841 | $15 million | -38% | 13F |
| Boxer Capital Management, LLC | 800,000 | $14 million | +0% | 13F |
| Aberdeen Group plc | 737,670 | $13 million | New | 13F |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 725,030 | $13 million | +1% | 13F |
| Connor, Clark & Lunn Investment Management Ltd. | 721,002 | $13 million | -17% | 13F |
| GREAT POINT PARTNERS LLC | 700,000 | $13 million | -60% | 13F |
| Balyasny Asset Management L.P. | 684,974 | $12 million | -38% | 13F |
| Qube Research & Technologies Ltd | 681,389 | $12 million | -3% | 13F |
| VANGUARD FIDUCIARY TRUST CO | 623,078 | $11 million | +6% | 13F |
| TWO SIGMA INVESTMENTS, LP | 593,435 | $11 million | +266% | 13F |
| DEUTSCHE BANK AG\ | 557,937 | $10 million | -56% | 13F |
| Rock Springs Capital Management LP | 499,764 | $9 million | +0% | 13F |
| ADAR1 Capital Management, LLC | 494,378 | $9 million | -51% | 13F |
| Nantahala Capital Management, LLC | 486,684 | $9 million | -9% | 13F |
| FEDERATED HERMES, INC. | 462,205 | $8 million | +27% | 13F |
| Nearwater Capital Markets, Ltd | 425,000 | $8 million | New | 13F |
| Parkman Healthcare Partners LLC | 398,782 | $7 million | -36% | 13F |
| HighVista Strategies LLC | 386,080 | $7 million | +10% | 13F |
| STEMPOINT CAPITAL LP | 384,304 | $7 million | -43% | 13F |
| Logos Global Management LP | 350,000 | $6 million | -50% | 13F |
| Trexquant Investment LP | 349,439 | $6 million | New | 13F |
| Nuveen, LLC | 330,521 | $6 million | +25% | 13F |
| Ensign Peak Advisors, Inc | 305,441 | $5 million | New | 13F |
| JANE STREET GROUP, LLC | 299,565 | $5 million | New | 13F |
| Tetragon Partners GP Ltd | 297,926 | $5 million | -6% | 13F |
| JUPITER ASSET MANAGEMENT LTD | 274,944 | $5 million | -54% | 13F |
| Bank of New York Mellon Corp | 274,435 | $5 million | +9% | 13F |
| UBS Group AG | 271,881 | $5 million | -16% | 13F |
| FIRST TRUST ADVISORS LP | 254,587 | $5 million | New | 13F |
| SummitTX Capital, L.P. | 227,690 | $4 million | +0% | 13F |
| WELLINGTON MANAGEMENT GROUP LLP | 212,842 | $4 million | -12% | 13F |
| Cormorant Asset Management, LP | 200,000 | $4 million | -43% | 13F |
| Aldebaran Capital, LLC | 195,892 | $4 million | -1% | 13F |
| Walleye Capital LLC | 186,588 | $3 million | +202% | 13F |
| ORBIMED ADVISORS LLC | 183,400 | $3 million | New | 13F |
| CITADEL ADVISORS LLC | 178,686 | $3 million | -57% | 13F |
| D. E. Shaw & Co., Inc. | 174,285 | $3 million | +135% | 13F |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 173,407 | $3 million | +10% | 13F |
| ACUTA CAPITAL PARTNERS, LLC | 168,115 | $3 million | +11% | 13F |
| NORGES BANK | 159,900 | $3 million | New | 13F |
| Alpha Wave Global, LP | 155,422 | $3 million | +9% | 13F |
| Swiss National Bank | 144,200 | $3 million | +11% | 13F |
| PFM Health Sciences, LP | 143,700 | $3 million | -1% | 13F |
| Invesco Ltd. | 139,942 | $3 million | -18% | 13F |
| WELLS FARGO & COMPANY/MN | 128,164 | $2 million | +71% | 13F |
| AMERIPRISE FINANCIAL INC | 125,484 | $2 million | New | 13F |
| Lighthouse Investment Partners, LLC | 122,909 | $2 million | New | 13F |
| Ikarian Capital, LLC | 117,500 | $2 million | New | 13F |
| RHUMBLINE ADVISERS | 112,920 | $2 million | +4% | 13F |
| ALPS ADVISORS INC | 112,447 | $2 million | +25% | 13F |
| Elmind Capital, LP | 112,000 | $2 million | +0% | 13F |
| Campbell & CO Investment Adviser LLC | 100,963 | $2 million | +86% | 13F |
| Affinity Asset Advisors, LLC | 98,999 | $2 million | New | 13F |
| Russell Investments Group, Ltd. | 87,574 | $2 million | +48% | 13F |
| Quantinno Capital Management LP | 80,850 | $1 million | New | 13F |
| ALLIANCEBERNSTEIN L.P. | 104,400 | $1 million | +29% | 13F |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 79,872 | $1 million | +23% | 13F |
| 1492 Capital Management LLC | 79,751 | $1 million | New | 13F |
| CITIGROUP INC | 68,684 | $1 million | +116% | 13F |
| Schonfeld Strategic Advisors LLC | 66,804 | $1 million | -14% | 13F |
| STATE OF WISCONSIN INVESTMENT BOARD | 61,278 | $1 million | -15% | 13F |
| Corient Private Wealth LP | 59,322 | $1 million | New | 13F |
| Moody Aldrich Partners LLC | 57,802 | $1 million | New | 13F |
| VANGUARD ASSET MANAGEMENT, Ltd | 56,948 | $1 million | +32% | 13F |
| Legal & General Group Plc | 56,477 | $1 million | +1% | 13F |
| BARCLAYS PLC | 56,258 | $1 million | -94% | 13F |
| MetLife Investment Management, LLC | 55,700 | $1 million | +8% | 13F |
| Hudson Bay Capital Management LP | 50,000 | $898,000 | New | 13F |
| Vanguard Global Advisers, LLC | 47,851 | $859,404 | +0% | 13F |
| FOX RUN MANAGEMENT, L.L.C. | 44,817 | $804,913 | New | 13F |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 42,351 | $760,624 | 0% | 13F |
| Aquatic Capital Management LLC | 39,425 | $708,073 | New | 13F |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 37,828 | $679,391 | -2% | 13F |
Questions and answers
- How many institutions hold Amylyx Pharmaceuticals, Inc.?
- 207 managers reported Amylyx Pharmaceuticals, Inc. on Form 13F for the quarter ended 30 June 2026, against 171 the quarter before.
- Who is the largest institutional holder of Amylyx Pharmaceuticals, Inc.?
- FMR LLC, with 16,727,909 shares worth $300 million on its 13F for Q2 2026.
- How many institutions bought or sold out of Amylyx Pharmaceuticals, Inc. in Q2 2026?
- 51 managers reported a new position and 15 reported none after holding it the quarter before.
Source: SEC EDGAR, Form 13F (public domain). Counts and values as filed. Cite this page: Tamarly Intelligence, "Who holds Amylyx Pharmaceuticals, Inc., Q2 2026", https://app.tamarly.ai/holders/amylyx-pharmaceuticals, built from SEC EDGAR.
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